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This antibody reacts weakly on human brain tissue.
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate receptor; Metabotropic glutamate receptor 6; mGluR6
Gene Aliases: BC021919; Gm3; Gprc1f; Grm6; Mglur6; nerg1; nob2; nob3; nob4
UniProt ID: (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Rat) 24419, (Mouse) 108072
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