Product References
Analysis of the Expression Pattern of Cajal-Retzius Cell Markers in the Xenopus laevis Forebrain.
Brain, behavior and evolution
Jiménez S,Moreno N
MA5-14117 was used in Immunohistochemistry to show that in anurans there are different subtypes and progenitor domains of Cajal-Retzius cells, which probably contribute to the cortical regional specification and territory-specific properties.
Thu Jun 02 00:00:00 EDT 2022
Early dorsomedial tissue interactions regulate gyrification of distal neocortex.
Nature communications
Chizhikov VV,Iskusnykh IY,Steshina EY,Fattakhov N,Lindgren AG,Shetty AS,Roy A,Tole S,Millen KJ
MA5-14117 was used in Immunohistochemistry to uncover early mesenchymal-neuroepithelial interactions that have long-range effects on neocortical gyrification and shows that lissencephaly in mice is actively maintained via redundant genetic regulation of dorsal midline development and signaling.
Fri Nov 15 00:00:00 EST 2019
SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity.
EMBO reports
Funato K,Hayashi T,Echizen K,Negishi L,Shimizu N,Koyama-Nasu R,Nasu-Nishimura Y,Morishita Y,Tabar V,Todo T,Ino Y,Mukasa A,Saito N,Akiyama T
MA5-14117 was used in Western Blotting to study SIRT2 regulation of p73 in glioblastoma cells.
Thu Nov 01 00:00:00 EDT 2018
E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis.
Cell death and differentiation
Liu J,Zhang C,Wang XL,Ly P,Belyi V,Xu-Monette ZY,Young KH,Hu W,Feng Z
MA5-14117 was used in Western Blotting to identify E3 ubiquitin ligase, TRIM32, as a novel p53 target gene and negative regulator to regulate p53-mediated stress responses.
Sat Nov 01 00:00:00 EDT 2014
The differential effects of wild-type and mutated K-Ras on MST2 signaling are determined by K-Ras activation kinetics.
Molecular and cellular biology
Romano D,Maccario H,Doherty C,Quinn NP,Kolch W,Matallanas D
MA5-14117 was used in western blot to study the role of altered K-Ras activation kinetics in the differential effects of wild-type and mutant K-Ras on MST2 pathways
Wed May 01 00:00:00 EDT 2013
TAp73β-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics.
Oncotarget
Rodhe J,Kavanagh E,Joseph B
MA5-14117 was used in western blot to study the role of p57Kip2-mediated modulation of the cytoskeleton in the mechanism by which TAp73-beta inhibits cell migration
Fri Feb 01 00:00:00 EST 2013
IkappaB kinase beta promotes cell survival by antagonizing p53 functions through DeltaNp73alpha phosphorylation and stabilization.
Molecular and cellular biology
Accardi R,Scalise M,Gheit T,Hussain I,Yue J,Carreira C,Collino A,Indiveri C,Gissmann L,Sylla BS,Tommasino M
MA5-14117 was used in western blot to study the role of IKKbeta-mediated phosphorylation and stabilization of deltaNp73alpha in antagonizing p53 function and enhancing cell survival
Wed Jun 01 00:00:00 EDT 2011
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway.
Genes & development
Wilhelm MT,Rufini A,Wetzel MK,Tsuchihara K,Inoue S,Tomasini R,Itie-Youten A,Wakeham A,Arsenian-Henriksson M,Melino G,Kaplan DR,Miller FD,Mak TW
MA5-14117 was used in immunocytochemistry to investigate the effect of delta Np73 on the induction of DNA damage response in vivo
Mon Mar 15 00:00:00 EDT 2010
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.
Molecular cell
Lapi E,Di Agostino S,Donzelli S,Gal H,Domany E,Rechavi G,Pandolfi PP,Givol D,Strano S,Lu X,Blandino G
MA5-14117 was used in western blot to study the role of PML, YAP, and p73 in the regulation of apoptotic process
Fri Dec 26 00:00:00 EST 2008
Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Inoue T,Ogawa M,Mikoshiba K,Aruga J
MA5-14117 was used in immunohistochemistry to detect the role of Zic in cortical lamination and its implication in type II lissencephaly
Wed Apr 30 00:00:00 EDT 2008
Sp1-like sequences mediate human caspase-3 promoter activation by p73 and cisplatin.
The FEBS journal
Sudhakar C,Jain N,Swarup G
MA5-14117 was used in western blot to study the role of Sp1-like sequences in human caspase-3 promoter activation by p73 and cisplatin
Thu May 01 00:00:00 EDT 2008
Resistance of mitochondrial p53 to dominant inhibition.
Molecular cancer
Heyne K,Schmitt K,Mueller D,Armbruester V,Mestres P,Roemer K
MA5-14117 was used in western blot to examine the dominant inhibition of p53 mutation
Thu Jun 12 00:00:00 EDT 2008
p73 expression in medulloblastoma: TAp73/DeltaNp73 transcript detection and possible association of p73alpha/DeltaNp73 immunoreactivity with survival.
Acta neuropathologica
Zitterbart K,Zavrelova I,Kadlecova J,Spesna R,Kratochvilova A,Pavelka Z,Sterba J
MA5-14117 was used in immunohistochemistry to investigate the expression of p73 in medulloblastoma specimens
Sat Dec 01 00:00:00 EST 2007
Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes.
Development (Cambridge, England)
Lee J,Basak JM,Demehri S,Kopan R
MA5-14117 was used in immunohistochemistry to study the mechanism underlying the different proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes
Wed Aug 01 00:00:00 EDT 2007
p53 dependent and independent sensitivity to oxaliplatin of colon cancer cells.
Biochemical pharmacology
Toscano F,Parmentier B,Fajoui ZE,Estornes Y,Chayvialle JA,Saurin JC,Abello J
MA5-14117 was used in western blot to study the p53-dependent and -independent sensitivity to oxaliplatin of colon cancer cells
Wed Aug 01 00:00:00 EDT 2007
S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.
Oncogene
Lapi E,Iovino A,Fontemaggi G,Soliera AR,Iacovelli S,Sacchi A,Rechavi G,Givol D,Blandino G,Strano S
MA5-14117 was used in western blot to investigate the regulatory effects of p53 homologues on S100A2 transcription during keratinocyte differentiation
Thu Jun 22 00:00:00 EDT 2006
Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order.
Development (Cambridge, England)
Yoshida M,Assimacopoulos S,Jones KR,Grove EA
MA5-14117 was used in immunohistochemistry to investigate the influence of Cajal-Retzius cell reduction on the development of neocortical layer order
Wed Feb 01 00:00:00 EST 2006
MDM2 is required for suppression of apoptosis by activated Akt1 in salivary acinar cells.
Molecular and cellular biology
Limesand KH,Schwertfeger KL,Anderson SM
MA5-14117 was used in western blot to study the role of MDM2 in the suppression of apoptosis by activated Akt1 in salivary acinar cells
Fri Dec 01 00:00:00 EST 2006
Over-expression of p73beta results in apoptotic death of post-mitotic hNT neurons.
Journal of the neurological sciences
Jiang Y,Lo W,Akhmametyeva EM,Chang LS
MA5-14117 was used in western blot to study the role of p73beta overexpression in apoptotic death of post-mitotic hNT neurons
Sun Jan 15 00:00:00 EST 2006
New antibodies recognizing p73: comparison with commercial antibodies.
Biochemical and biophysical research communications
Sayan AE,Paradisi A,Vojtesek B,Knight RA,Melino G,Candi E
MA5-14117 was used in western blot to compare three new anti-p73 antibodies with those commercially available
Fri Apr 29 00:00:00 EDT 2005
Developmental roles of p73 in Cajal-Retzius cells and cortical patterning.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Meyer G,Cabrera Socorro A,Perez Garcia CG,Martinez Millan L,Walker N,Caput D
MA5-14117 was used in immunohistochemistry to study the role of p73 in brain development
Wed Nov 03 00:00:00 EST 2004
ASPP1 and ASPP2: common activators of p53 family members.
Molecular and cellular biology
Bergamaschi D,Samuels Y,Jin B,Duraisingham S,Crook T,Lu X
MA5-14117 was used in western blot to study the role of ASPP1 and ASPP2 in the p53 signaling pathway
Sun Feb 01 00:00:00 EST 2004
p73 tumor-suppressor activity is impaired in human thyroid cancer.
Cancer research
Frasca F,Vella V,Aloisi A,Mandarino A,Mazzon E,Vigneri R,Vigneri P
MA5-14117 was used in immunoprecipitation to study the p73 tumor-suppressor activity in human thyroid cancer
Mon Sep 15 00:00:00 EDT 2003
p73 Overexpression and angiogenesis in human colorectal carcinoma.
Japanese journal of clinical oncology
Guan M,Peng HX,Yu B,Lu Y
MA5-14117 was used in immunohistochemistry to study the expression of p73 in colorectal cancer and its potential role in tumor angiogenesis
Thu May 01 00:00:00 EDT 2003
Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function.
The Journal of biological chemistry
Vella V,Zhu J,Frasca F,Li CY,Vigneri P,Vigneri R,Wang JY
MA5-14117 was used in western blot to investigate the effect of c-Abl nuclear exclusion on p73 function in human cancers
Fri Jul 04 00:00:00 EDT 2003
Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.
The Journal of biological chemistry
Kim EJ,Park JS,Um SJ
MA5-14117 was used in western blot to study the interaction of HIPK2 with p73 and other p53 family members and its potential role in regulating apoptosis and the cell cycle
Fri Aug 30 00:00:00 EDT 2002