Fermentation production facilities can utilize the Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) instead of traditional stainless steel cleaning-in-place/sterilization-in-place (CIP/SIP) fermentor vessels without modifying their existing procedures. As expression systems are moved to production volumes, they can easily be scaled from a benchtop fermentor (or flask) to the S.U.F. Unlike hybrid solutions – cell culture bioreactors converted to fermentation systems – the S.U.F. has been specifically designed to meet the rigorous demands of microbial fermentation and delivers yields that are comparable to traditional CIP/SIP systems.