Trimethylphosphine oxide

Trimethylphosphine oxide is a common side product in organic synthesis, including the Wittig, Staudinger, Mitsunobu reactions and also in the manufacture of triphenylphosphine. It is a popular reagent to induce the crystallization of various chemical compounds. It acts as an excellent ligand for hard metal centers. It can react with 9-methyl-9-azonianthracene methyl sulfate to get (10-methyl-9,10-dihydro-acridin-9-yl)-phosphonic acid dimethyl ester using sodium iodide and acetonitrile as solvent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.