Thermo Scientific™

Dionex™ ICS-5000+ Hybrid HPIC™ System

Related applications:

Industrial Chromatography

Get best-in-class resolution, sensitivity, and throughput for even the most complex ICxIC (2D-IC) methods and trace level analyses. The versatile Thermo Scientific™ Dionex™ ICS-5000+ Hybrid HPIC™ System provides faster separations without compromising resolution, thanks to its dual high-pressure channels: one optimized for capillary flow rates, the other for standard (4mm) or microbore (2mm). You'll save time and improve reproducibility with precise, automatic eluent generation and sample preparation. Choose from a wide variety of chemistries, detectors, and automation options to fit your needs.

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Built on our top-of-the-line IC platform, this system provides the high performance, convenience, and flexibility of the Thermo Scientific™ Dionex™ ICS-5000+ HPIC System with the power of parallel analytical and capillary channels.

Run two analyses concurrently on a single sample, analyze two samples, or perform advanced ICxIC (2D-IC) techniques. The Dionex ICS-5000+ Hybrid HPIC System is ideally suited for trace level determinations with high matrix concentrations, using a standard or microbore column in the first dimension to separate analytes from matrix, followed by a capillary separation in the second dimension. This method provides high sensitivity, enabling conductivity detection limits to rival those of mass spectrometry.

High Pressure, High Performance
  • Fast, sensitive separations without sacrificing resolution—up to two times faster still with Fast IC columns
  • Outstanding resolution using columns with small-diameter particles, thanks to high-pressure capability
  • Continuous operation at up to 5000psi when configured as a Reagent-Free™ IC (RFIC™) system
  • Optimized peak resolution with a choice of isocratic and electrolytic gradient separations on either channel, or optional quaternary low pressure gradients on the standard/microbore channel
  • Flexible support for standard bore (3-7mm I.D.)and microbore (1-3mm I.D.) columns on one channel and capillary columns (0.2-0.6mm I.D.) on the other
  • Wide variety of chemistries available in Thermo Scientific™ standard bore, microbore, capillary, and Fast IC columns
  • Flexible, easy to configure, modular design

The Capillary Advantage

The capillary channel in this hybrid system presents added advantages:

  • Always ready with 24/7 uptime and minimal calibration and equilibration time
  • Up to 18 months of continuous operation on one Eluent Generation cartridge
  • Small dead volumes for minimized peak dispersion and increased signal-to-noise ratio
  • Reduced eluent disposal costs—only 15mL/day for continuous operation at 10µL/min
  • Enhanced ease-of-use with Thermo Scientific™ Dionex™ IC Cube™ capillary consumable cartridges

Choose from a broad variety of Dionex ICS-5000+ modules and related products. See the Dionex ICS-5000+ HPIC System Product Features for a full list.

Sample Preparation and Automation Solutions

Dionex autosamplers integrate seamlessly with all Dionex ICS-5000+ HPIC systems, providing effortless automation and advanced sample preparation capabilities.