Get industry-leading, ultra-high resolution of labeled and native glycans for structural characterization and quantification using the Thermo Scientific™ GlycanPac™ AXR-1 LC Columns. This high-performance, silica-based chromatography column achieves mixed-mode separation using a combination of charge, isomer structure, and size. Now there's a column with unique selectivity to analyze biologically important glycans. The GlycanPac AXR-1 column is available in multiple HPLC and UHPLC formats and is compatible with fluorescence or mass spectrometry (MS) detection.
Ultra-high resolution and selectivity of glycans are attributed to the GlycanPac AXR-1 column's innovative mixed-mode surface chemistry, which combines:
This high-purity spherical silica column is designed and tested for HPLC and UHPLC methods using either fluorescence or MS detection applications. The GlycanPac AXR-1 column uses volatile aqueous buffers (e.g., ammonium acetate or ammonium formate) and acetonitrile, presenting the eluting glycans ready for introduction into MS instruments.Available in Multiple Formats