Geneticin® Selective Antibiotic (G418 Sulfate) is produced by the bacterium Micromonospora rhodorangea and acts by binding the ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells. Resistance to Geneticin® Selective Antibiotic (G418 Sulfate) is conferred by the E. coli APH (3’) – I and APH (3’) – II resistance genes. Gibco® Geneticin® Selective Antibiotic (G418 Sulfate) is used as a selective antibiotic in the concentration range of 100 - 200 µg/ml for bacteria, or 200 – 500 µg/ml for most mammalian cells. This product is supplied as a 50 mg/ml solution in water. We offer a variety of cell culture antibiotics for your convenience.
Product Use For Research Use Only: Not intended for animal or human diagnostic or therapeutic use.
Dual-Site cGMP Manufacturing and Quality Standard Gibco® Geneticin® Selective Antibiotic (G418 Sulfate) is manufactured at a cGMP compliant facility, located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards. For supply chain continuity, we offer an identical Gibco® Geneticin® Selective Antibiotic (G418 Sulfate) product made in our Scotland facility (10131-019). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard.
For Research Use Only. Not for use in diagnostic procedures.
Eukaryotic Selection⁄Stable Cell Line Generation
Eukaryotic Cell, Prokaryotic Cell
Contents & Storage
Storage conditions: 2 to 8°C Shipping conditions: Ambient Shelf life: 24 months from date of manufacture