Thermo Scientific™

α-Synuclein Mouse mAb (clone LB509), concentrate

Catalog number: 180215
Thermo Scientific™

α-Synuclein Mouse mAb (clone LB509), concentrate

Catalog number: 180215
Catalog Number
180215
also known as 18-0215
Unit Size
1 mL
Price (USD)
538.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
180215
also known as 18-0215
1 mL
538.00
Your Price:
***
Product Overview
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Synucleins (α, β, and γ) are a family of cytoplasmic proteins found predominantly, and abundantly, in the brain with cellular distribution concentrated in presynaptic nerve terminals, primarily near vesicles. Synucleins are thought to be involved in neuronal plasticity, synaptic function, and neurodegenerative disease. α-Synuclein (∼18 kDa) is abundant in Lewy Bodies in sporadic Parkinson's Disease (PD) and Dementia with Lewy Bodies (DLB). It has been reported that the NAC fragment from α-synuclein is a major component of amyloid plaques in Alzheimer's Disease. LB509 reacts with α-synuclein but not SM-synuclein. Reactivity has not been observed with γ-synuclein. Positive tissue: Parkinson's disease tissue.

Clone/PAD: LB509

Immunogen: Lewy Bodies purified from patients suffering dementia with Lewy Bodies

Specificity: α-Synuclein

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Not required, Enzyme Digestion: Not required

Expected Staining Pattern: Cytoplasmic
For In Vitro Diagnostic Use.

Specifications

Antibody Conjugate
Unconjugated
Clonality
Monoclonal
Host abrv
Ms
Label Type
Unconjugated
Label or Dye
Unconjugated
Reactivity
Human
Reactivity abrv
Hu
Shipping Condition
Wet Ice
Sub Class Isotype
IgG1, kappa
Target Gene
alpha-Synuclein
Validated Application
Immunohistochemistry (FFPE)
Validated Application abrv
IHC (FFPE)
Dilution
Concentrate Antibody
Host Species
Mouse
Gene ID (Entrez)
6622

Contents & Storage

Store in refrigerator (2–8°C).

Shelf life: 18 months from date of manufacture

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