Bcl-10 Mouse mAb (clone151), concentrate

Catalog number: 180275

 Related applications: Anatomical Pathology

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This monoclonal antibody reacts with Bcl-10. Bcl-10 is an apoptotic regulatory molecule identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. It is also expressed both in normal lymphoid tissue but doesn't exhibit cross reaction with other tissues except breast. In non-malignant B-cell follicles, the protein is expressed in the cytoplasm of the germinal center B-cells, while in MALT lymphomas with t(1;14)(p22;q32), Bcl-10 expression could be detected both in nucleus and cytoplasm. Western blotting analysis showed that Bcl-10 was present as a 32 kDa band. Immunogen source: Recombinant full length human Bcl-10 fusion protein. Positive tissue: MALT lymphoma with t(1:14)(p22;q32) translocation/tonsil.

Clone/PAD: 151

Immunogen: Recombinant full length human BCL-10 fusion protein

Specificity: Bcl-10

Reactivity: Human

Applications: Immunohistochemistry (FFPE, Frozen)

Pretreatment: Epitope Retrieval: Required (Citrate Buffer pH 6.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Cytoplasmic and/or nuclear
For In Vitro Diagnostic Use.


Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Target Gene: Bcl-10
Gene ID: 8915
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).


Manuals & protocols