Calretinin Mouse mAb (clone Z11-E3), concentrate

Catalog number: 180291

 Related applications: Anatomical Pathology

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Description

This monoclonal antibody reacts with human calretinin. Calretinin is abundantly expressed in central and peripheral neural tissues especially in the retina and neurons of the sensory pathways. Calretinin is also expressed in normal and reactive mesothelial cell lining of all serosal membranes, eccrine glands of the skin, convoluted tubules of the kidney, Leydig and Sertoli cells of the testis, endometrium and ovarian stromal cells and adrenal cortical cells. This antibody is useful as part of an immunohistochemical marker panel to distinguish mesothelioma from adenocarcinoma. The combination of calretinin and E-Cadherin was shown to have high sensitivity and specificity in differentiating malignant mesothelioma from metastatic adenocarcinoma to the pleura. Positive tissue: Mesothelioma.

Clone/PAD: Z11-E3

Immunogen: Full length recombinant mouse Calretinin protein

Specificity: Calretinin

Reactivity: Human, Mouse

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (EDTA solution, pH 8.0), Enzyme Digestion: Not required

Expected Staining Pattern: Nuclear and cytoplasmic
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human, Mouse
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG2b
Clonality: Monoclonal
Target Gene: Calretinin
Gene ID: 794
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

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