SKP2 (S-Phase Kinase-Associated Protein 2) Mouse Monoclonal Antibody (clone 2C8D9), Concentrate

Catalog number: 187334

 Related applications: Anatomical Pathology

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Description

SKP2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. In tumor tissues, SKP2 is expressed widely, such as colon mucinous carcinoma, gastric adenocarcinoma, breast cancer, melanoma, prostate adenocarcinoma, with particularly higher expression on lung adenocarcinoma, lung squamous carcinoma, squamous carcinoma of cervix, endometrial carcinoma, ovary serous carcinoma and leiomyosarcoma. A recent study suggests that SKP2 plays a role in oncogenesis and is involved in the pathogenesis of lymphomas. Positive tissue: Breast cancer

Clone/PAD: 2C8D9

Immunogen: Recombinant human SKP2

Specificity: SKP2

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (EDTA, pH 8.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Nuclear
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG1
Clonality: Monoclonal
Target Gene: SKP2 (S-Phase Kinase-Associated Protein 2)
Gene ID: 6502
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

Documents

Manuals & protocols