MGMT Mouse Monoclonal Antibody (clone MT23.2), Concentrate

Catalog number: 187337

 Related applications: Anatomical Pathology

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Description

This antibody reacts specifically with MGMT protein. O6-methylguanine-DNA methyltransferase (MGMT) is a ubiquitous 22 kDa DNA repair protein, involved in the repair of mutagenic, carcinogenic, and cytotoxic O6-alkylguanine adducts, including primary alkyl adducts, induced by the chloroethylating and methylating agents used in the treatment of cancers. Positive tissue: Breast cancer/lung cancer/ovarian cancer.

Clone/PAD: MT23.2

Immunogen: Recombinant human MGMT

Specificity: MGMT (O6-methylguanine-DNA methyltransferase)

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (EDTA, pH 8.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Nuclear
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG2b
Clonality: Monoclonal
Target Gene: MGMT
Gene ID: 4255
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

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