Rabbit anti-Claudin-3-Concentrate

Catalog number: 187340

 Related applications: Anatomical Pathology

Error loading your content!

  Catalog number
Select a plan
Unit size
Price ({{currency}}) Qty
{{product.sku}} {{product.sku}}
also known as {{product.formattedSku}} 
{{product.availability.message}}
Pro add-ons

Your on-site stock

›› {{supplyCenter.scName}}({{scProduct.stockOnHand}} In stock)
›› {{supplyCenter.scName}}(Out of stock)
›› {{supplyCenter.scName}}
This item is not currently available on-site. Depending on your Supply Center settings you may be able to add the item to cart above else use the Order Non-Stocked Items' tab on the Supply Center home page.
Back to top

Description

Tight junctions are specialized regions of cell-cell contact that are particularly abundant in luminal epithelial cell sheets. A study showed that Claudin-3 was found to be present or secreted by many of the genes up-regulated in ovarian cancer. Furthermore, in a recent study Claudin-3 expression was shown capable of mediating Clostridium perfringens enterotoxin (CPE) binding and cytolysis; this suggests that Claudin-3 could be a potential therapeutic strategy for prostate cancer. Positive tissue: Colon.

Clone/PAD: Z23.JM

Immunogen: A synthetic peptide from the C-terminus of mouse Claudin-3

Specificity: Claudin-3

Reactivity: Human, Mouse

Applications: Western Blot and Immunohistochemistry

Pretreatment: Epitope Retrieval: Required (Citrate buffer, pH 6.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Predominately membrane staining. Certain cancer tissues show cytoplasmic staining in addition to membrane staining.
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human, Mouse
Validated Application: Immunohistochemistry, Immunohistochemistry (FFPE), Western Blot
Host Species: Rabbit
Clonality: Polyclonal
Target Gene: Claudin-3
Gene ID: 1365
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

Documents

Manuals & protocols