Claudin-1 Rabbit Polyclonal Antibody (clone JAY.8), Concentrate

Catalog number: 187362

 Related applications: Anatomical Pathology

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Description

Claudin-1 is a tight junction protein whose expression is very low or absent in breast cancer cell lines and tissues, microvessels of glioblastoma multiforme, but is increased in colon carcinoma as compared to adjacent noncancerous mucosa. Claudin-1 may also be a useful IHC marker in the diagnosis pf perineurioma. Positive tissue: Normal skin

Clone/PAD: JAY.8

Immunogen: Synthetic peptide derived from the C-terminus of human claudin-1

Specificity: Claudin-1

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (EDTA, pH 8.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Predominantly cytoplasmic with some membrane and nuclear
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Rabbit
Clonality: Polyclonal
Target Gene: Claudin-1
Gene ID: 9076
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

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