COX-2 Mouse Monoclonal Antibody (clone COX 229), Concentrate

Catalog number: 187379

 Related applications: Anatomical Pathology

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This antibody reacts specifically with COX-2 protein. Cyclooxygenase (COX) is a membrane-bound enzyme, which has a molecular weight of 72 kDa. It is an enzyme that catalyzes the synthesis of cyclic endoperoxides from arachidonic acid to form prostaglandins (lipid-soluble, homone-like regulatory molecules). Two isoforms of COX have been identified and are known as COX-1 and COX-2. COX-2 is dimeric and is the inducible (i.e., sites of inflammation) isoform of cyclooxygenase.Positive tissue: Colon carcinoma.

Clone/PAD: COX 229

Immunogen: Synthetic peptide from human COX-2

Specificity: COX-2

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (Citrate Buffer, pH 6.0), Enzyme Digestion: Not required

Expected Staining Pattern: Cytoplasm
For In Vitro Diagnostic Use.


Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG1, kappa
Clonality: Monoclonal
Target Gene: COX-2
Gene ID: 5743
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).


Manuals & protocols