EZH2 Rabbit Polyclonal Antibody (clone ZMD.309), Concentrate

Catalog number: 187395

 Related applications: Anatomical Pathology

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Description

EZH2, also known as ENX-1, is ubiquitously expressed during early embryogenesis, and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. EZH2 is involved in the progression of prostate cancer, and may be a marker that distinguishes prostate cancers at risk of lethal progression from indolent prostate cancer. EZH2 has been identified as a marker of aggressive breast cancer and a promoter of neoplastic transformation of breast epithelial cells. Positive tissue: Breast cancer

Clone/PAD: ZMD.309

Immunogen: Synthetic peptide of human EZH2

Specificity: EZH2

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: HIER (Citrate buffer, pH 6.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Mainly nuclear
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Rabbit
Clonality: Polyclonal
Target Gene: EZH2
Gene ID: 2146
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 0.5 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

Documents

Manuals & protocols