Thermo Scientific Pierce Sulfo-KMUS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).
Features of Sulfo-KMUS:
• Reactive groups:sulfo-NHS ester and maleimide • Reactive toward: amino and sulfhydryl groups • Long aliphatic spacer arm compared to Sulfo-GMBS • Sulfo-NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond • Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond • Non-cleavable • Water-soluble
Product References: Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.