Thermo Scientific™

Sulfo-KMUS (N-κ-maleimidoundecanoyl-oxysulfosuccinimide ester)

Catalog number:  21111

 Related applications:

Protein Labeling & Crosslinking

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Thermo Scientific Pierce Sulfo-KMUS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).

Features of Sulfo-KMUS:

Reactive groups: sulfo-NHS ester and maleimide
Reactive toward: amino and sulfhydryl groups
• Long aliphatic spacer arm compared to Sulfo-GMBS
• Sulfo-NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-soluble

Product References:
Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.


Crosslinker Type: Heterobifunctional
Labeling Method: Chemical Labeling
Product Line: Pierce™
Product Size: 50 mg
Solubility: Water
Spacer: Long

Contents & storage

Upon receipt store desiccated at 4°C. Product is shipped at ambient temperature.


Manuals & protocols