Thermo Scientific™

2'-OMe-Ac-C Phosphoramidite, standard grade, 28-400 finish bottle

Catalog number: 27-1823-11
Thermo Scientific™

2'-OMe-Ac-C Phosphoramidite, standard grade, 28-400 finish bottle

Catalog number: 27-1823-11
Catalog Number
27-1823-11
Unit Size
1 g
Price (USD)
57.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1823-111 g
57.00
Your Price:
***
Product Overview
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2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C42H52N5O9P
• Base—C
• Base Protection—Ac
• Formula weight—801.86 g/mol
• CAS number—199593-09-4
• HPLC purity—≥98.0%; Sum of PIII impurities (140-152ppm) ≤0.5%
31P NMR purity—≥98.0%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Format
Powder
For Use With (Equipment)
MerMade Synthesizers
Product Type
2in-OMe-Ac-C CEP
Nucleoside Type
Cytidine (C)
Reagent Features
2in-OMe modified, Fast deprotection
Shipping Condition
Room Temperature
Purity
98%
Reagent Type
Phosphoramidite
Grade
Standard
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).

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