2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20-mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
Features: • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite • Molecular formula—C48H54N7O8P • Base—A • Base Protection—Bz • Formula weight—887.97 g/mol • CAS number—110782-31-5 • HPLC purity—≥98.0%; Sum of non-primary peaks 140-152ppm: ≤0.5% • 31P NMR purity—≥98.0%
For Research Use Only. Not for use in diagnostic procedures.
For Use With (Equipment)
AKTA Synthesizers, Applied Biosystems Synthesizers