Thermo Scientific™

2'-OMe-C Phosphoramidite, TheraPure™ grade, 20-400 finish bottle

Catalog number: 27-2043-10
Thermo Scientific™

2'-OMe-C Phosphoramidite, TheraPure™ grade, 20-400 finish bottle

Catalog number: 27-2043-10
Catalog Number
27-2043-10
Unit Size
1 g
Price (USD)
61.25
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-2043-101 g
61.25
Your Price:
***
Product Overview
Figures
Videos
Documents
FAQ
Citations & References
Additional Information
Recommendations
2'-OMe-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C42H52N5O9P
• Base—C
• Base Protection—Ac
• Formula weight—801.86 g/mol
• CAS number—199593-09-4
• HPLC purity—≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
31P NMR purity—>99%; Sum of non-primary peaks at 140-152ppm ≤0.5%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Line
TheraPure™
Format
Powder
For Use With (Equipment)
Expedite Synthesizers
Product Type
2in-OMe-C CEP
Nucleoside Type
Cytidine (C)
Reagent Features
2in-OMe modified
Shipping Condition
Room Temperature
Purity
99%
Reagent Type
Phosphoramidite
Grade
TheraPure™
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).

Figures

Frequently asked questions (FAQs)

Citations & References