ProPac™ 3R SCX 3 μm HPLC Columns
ProPac™ 3R SCX 3 μm HPLC Columns
Thermo Scientific™

ProPac™ 3R SCX 3 μm HPLC Columns

Get the performance you need with ProPac™ 3R SCX HPLC columns. Suitable for charge variant separations and recommended for therapeutic proteins, mAbs, ADCs, and biosimilar proteins.
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Catalog NumberLength (Metric)Diameter (Metric)Flow Rate
43103-05206850 mm2 mm0.1 to 0.3 mL/min
43103-05406850 mm4 mm0.3 to 0.5 mL/min
43103-102068100 mm2 mm0.1 to 0.2 mL/min.
43103-104068100 mm4 mm0.3 to 0.5 mL/min.
Catalog number 43103-052068
Price (USD)/ Each
1,009.01
Add to cart
Length (Metric):
50 mm
Diameter (Metric):
2 mm
Flow Rate:
0.1 to 0.3 mL/min
Price (USD)/ Each
1,009.01
Add to cart
ProPac™ 3R SCX 3 μm HPLC Columns
Catalog number43103-052068
Price (USD)/ Each
1,009.01
-
Add to cart

Use Thermo Scientific™ ProPac™ 3R SCX 3 μm HPLC columns to provide the reproducibility, resolution, and robustness needed for protein characterization. These columns are ideal for charge variant analysis and recommended for use with therapeutic proteins, monoclonal antibodies (mAbs), antibody drug conjugates (ADCs), and biosimilar proteins.

Designed with bio-inert materials to reduce secondary interactions, our ProPac 3R SCX columns deliver the performance you need over a broad range of pH's, temperatures, and mobile phase compositions with excellent recovery and low carryover.

Suitable for use with mass spectrometry (MS).

Maximizing Reproducibility, Resolution, and Robustness

The ProPac 3R SCX 3 μm HPLC column is a strong cation-exchanger with a sulfonic acid functional group, suitable for use in biomolecule applications. These specialized ion-exchange chromatography columns provide qualitative and quantitative evaluation of charge variant analysis to biopharmaceutical scientists who need reproducible resolving capabilities when identifying and quantifying charge variant profiles of proteins.

Our ProPac 3R SCX columns offer superior performance for characterization of proteins including monoclonal antibodies (mAbs), therapeutic proteins, antibody drug conjugates (ADCs), and biosimilar proteins.

Column Features:

  • Ideal for characterization and quality control assessment of closely-related protein variants
  • Unequaled high-resolution separations
  • High-efficiency peaks with excellent recovery
  • Higher capacity than other columns based on nonporous particles
  • Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
  • Compatible with mass spectrometry (MS)

We recommend our CX-1 pH gradient buffers when using these columns with LC-UV/LC-FLD.

Specifications
Column FormatAnalytical Column
Diameter (Metric)2 mm
Flow Rate0.1 to 0.3 mL/min
Length (Metric)50 mm
Max. Pressure4500 psi (310 bar)
Mobile Phase CompatibilityRecommended for use with CX-1 pH buffers
Particle Size3 μm
pH2 to 12
Pore SizeNonporous
TemperatureAmbient to 60°C
Stationary PhaseProprietary
Product LineProPac
Packing MaterialMonodisperse Polymer Resin
Column TypeIon Exchange
PhaseStrong Cation Exchange
MaterialPEEK Hardware
TechniqueBio-LC
Unit SizeEach