MagMAX™ Express Magnetic Particle Processor (BR-Basic Research Customer) - FAQs

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21 product FAQs found

Do you have any recommendations for addressing the head position error of the MagMAX Express Magnetic Particle Processor?

Turn the machine off, and inspect it for any visible damage. Make sure the correct head is being used for the protocol being run. If the machine shows no visible damage, turn it back on. This should reset the machine. If the problem immediately occurs again, turn the machine off and gently move the magnetic head apparatus to the center of its travel path, then turn the machine on again. If the problem persists, the head may need to be realigned by a service call.

The MagMAX Express Magnetic Particle Processor will not pick up the tip comb. Any suggestions for what I should do?

A potential cause is that the plastic tip comb has warped slightly due to its design. This is why they are packed in pairs, so that they maintain their shape. Flex the backbone of the tip comb and try again.

What if the magnetic particles are attached to the tip combs after the run using the MagMAX Express Magnetic Particle Processor?

This happens sometimes, but it will not affect the yield because the sample has been released from the particles.

Can I stop in the middle of the run? What if power shuts off in the middle of the run when using the MagMAX Express Magnetic Particle Processor?

There is a pause function if you hit ‘stop' in the middle of a run. If you hit start again, the run continues. If you hit stop twice, the run stops completely. There is no way to begin a run in the middle of a protocol.

What if the magnetic particles remained in the sample well when using the MagMAX Express Magnetic Particle Processor?

If the starting material is too viscous, the magnetic rods will not be able to collect the particles. Dilute the sample and check that the sample has been properly homogenized and lysed.

What should I do if I forget to insert the tip combs into the tip comb holder in the MagMAX Express Magnetic Particle Processor?

The protocol will not start without the tip combs inserted into the tip comb holder.

What should I do if the magnet set is dirty in the MagMAX Express Magnetic Particle Processor?

Wipe the magnetic rods with a soft cloth or tissue paper soaked in a mild detergent solution, soap solution, or alcohol.

What magnetic stand should I purchase for manual extraction? Cat. No. AM10027 or Cat. No. AM10050?

It is a personal preference as to which magnetic stand to purchase. Cat. No. AM10027 can be easier if using a pipettor for liquid handling, as beads clump to the side, Cat. No. AM10050 if using a robotic liquid handler, as beads clump in a ring.

Is there a deep well MagMAX Express-24 version?

No, unfortunately not.

I want to process a large sample (e.g., 300µL or more)—which plate should I use for the MagMAX Magnetic Particle Processor?

Deep well plates are recommended. Use a deep well configuration for larger sample inputs (up to 400 µL).

Does the splashing by the tip comb cause cross-contamination?

Mixing with the tip comb is designed to occur below the liquid surface. This prevents aerosols and splashing from occurring when using the MagMAX Express instrument.

Are the volumes of reagents in each well critical when using MagMAX Express Magnetic Particle Processor?

We strongly recommend that you keep the specified volumes within the defined limits to avoid spillover of the reagents.

How long does it take the heater to warm up from room temperature to 80 degrees C for the MagMAX Express Magnetic Particle Processor?

The heating block warms up about 10 degrees C per minute, so it will take about 6 minutes.

How does the heating block work with the MagMAX Express-96 Magnetic Particle Processor?

The heating block is located inside the instrument and can be used automatically during the protocol. Both MagMAX Express-96 plates and PCR plates (skirted) can be heated using specially designed, interchangeable heating blocks. Any number of heating steps can be added to the protocol. During the protocol, when the protocol enters the heating step, the plate is automatically moved to the dedicated heating position for heating. After the heating step, the protocol continues automatically to the next step.
Note: No cooling steps can be added.

How strong are the MagMAX magnets? Can they, for example, disturb some sensitive equipment?

The MagMAX Express-96 system should not be kept in close proximity to magnetic tapes, computer discs, or other magnetic storage systems, such as credit cards, as these can be damaged by the strong magnetic field of the MagMAX Express-96 heads. Do not hold the MagMAX Express-96 heads close to a PC display, since this may cause damage to the display. Do not use metal tools when handling MagMAX Express-96 heads.
Warning: This product contains very strong permanent magnets. People wearing a pacemaker or metallic prosthesis should not use this product. A pacemaker or prosthesis may be affected or damaged if it comes in close contact with a strong magnetic field.

Will the magnet get weaker? If so, how long can they be used?

The MagMAX Express-96 magnets are made of material that is very stable. The magnetic field will not get weaker. However, extreme mechanical force or heating can cause damage to the magnets.
Note: It is very important to keep the MagMAX Express-96 heads away from each other and other magnets at all times. Clashing of the magnets together causes serious damage to the magnets.

Can I concentrate my sample during the run when using the MagMAX Express-96 Magnetic Particle Processor?

Yes. Both deep well plates and MagMAX Express-96 standard plates can be used during the same run. Therefore, it is possible to start the processing by using larger volumes (in a deep well plate) and elute the purified nucleic acid to a smaller volume (in a MagMAX Express-96 standard plate).

What plates can be used with the MagMAX Express-96 Magnetic Particle Processor?

The MagMAX Express-96 deep well plates (Cat. No. 4388476) and standard plates (Cat. No. 4388475) can be used with the instrument.

I am getting an error message with the MagMAX Express/KingFisher Flex instrument. What should I do?

Turn the instrument on and off to see whether the error message disappears. Alternatively, do a dry run without any samples. If the issue could be consumable dependent try a new set/lot of tip combs. If the error message repeatedly occurs, please contact Technical Support (techsupport@thermofisher.com).

What software can I use with the MagMAX-96 instrument?

The MagMAX-96 instrument is compatible with the old KingFisher software and the new BindIT software (designed for KingFisher Flex). We generally recommend using the BindIT software over the KingFisher software since it is the newer software and it is the only one that is compatible with Windows7 and newer Windows versions. The KingFisher software is only compatible with Windows XP.

What is the major difference between the KingFisher Flex and MagMAX Express-96 instruments?

- The KingFisher Flex instrument has the option of using a 24-Deep-Well head in addition to a 96-Deep-Well head.
- The KingFisher Flex instrument has a USB communications port, whereas the MagMAX Express-96 instrument only has a RS-232 port.
- The KingFisher Flex instrument uses snap-in heat blocks, while the heat blocks need to be screwed in for the MagMAX Express-96 instrument.
- Unlike the MagMAX Express-96 instrument, the KingFisher Flex instrument has a graphical user interface and expanded keypad (LCD screen).