44356 - Citations

44356 - Citations

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Abstract
A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.
AuthorsCopenhaver PF, Anekonda TS, Musashe D, Robinson KM, Ramaker JM, Swanson TL, Wadsworth TL, Kretzschmar D, Woltjer RL, Quinn JF
JournalDis Model Mech
PubMed ID21596710
A growing body of evidence supports the 'calcium hypothesis' of Alzheimer's disease (AD), which postulates that a variety of insults might disrupt the homeostatic regulation of neuronal calcium (Ca(2+)) in the brain, resulting in the progressive symptoms that typify the disease. However, despite ongoing efforts to develop new methods for ... More