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Citas y referencias (1)

AB-TUBE-ANTI--MYC

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Número de catálogo 460603
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AB-TUBE-ANTI--MYC
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Unit Size1 each

Citations & References (1)

Citations & References
Abstract
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
Authors:Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I,
Journal:Neuron
PubMed ID:12062018
'PQBP-1 was isolated on the basis of its interaction with polyglutamine tracts. In this study, using in vitro and in vivo assays, we show that the association between ataxin-1 and PQBP-1 is positively influenced by expanded polyglutamine sequences. In cell lines, interaction between the two molecules induces apoptotic cell death. ... More