Thermo Scientific™

SMART Digest™ RNase Kits

Catalog number: 60120-102
Thermo Scientific™

SMART Digest™ RNase Kits

Catalog number: 60120-102

Obtain high-quality analytical results from mRNA digestions using Thermo Scientific™ SMART Digest™ RNase Kits. A significant advance in sample preparation for oligonucleotide mapping and quantitation, these kits provide fast and simple mRNA digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that is compatible with automation.

 
Catalog Number
60120-102
Unit Size
Each
Cleavage
Degrades single-stranded RNA at C and U residues
Enzyme
RNase A
Price (USD)
Full specifications
Quantity
CleavageDegrades single-stranded RNA at C and U residues
EnzymeRNase A
FormatBulk Magnetic SMART Digest Resin
For Use With (Application)Oligonucleotide Mapping
Product LineSMART Digest
TypeRNA Digestion
IncludesBulk Magnetic SMART Digest Resin, SMART Digest Buffer
Unit SizeEach
Catalog Number
Unit Size
Each
Cleavage
Degrades single-stranded RNA at G residues
Enzyme
RNase T1
Price (USD)
Full specifications
Quantity
CleavageDegrades single-stranded RNA at G residues
EnzymeRNase T1
FormatBulk Magnetic SMART Digest Resin
For Use With (Application)Oligonucleotide Mapping
Product LineSMART Digest
TypeRNA Digestion
IncludesBulk Magnetic SMART Digest Resin, SMART Digest Buffer
Unit SizeEach
Showing 2 of 2
Catalog NumberSpecificationsUnit SizeCleavageEnzymePrice (USD)Quantity
60120-102Full specifications
EachDegrades single-stranded RNA at C and U residuesRNase A
CleavageDegrades single-stranded RNA at C and U residues
EnzymeRNase A
FormatBulk Magnetic SMART Digest Resin
For Use With (Application)Oligonucleotide Mapping
Product LineSMART Digest
TypeRNA Digestion
IncludesBulk Magnetic SMART Digest Resin, SMART Digest Buffer
Unit SizeEach
60120-101Full specifications
EachDegrades single-stranded RNA at G residuesRNase T1
CleavageDegrades single-stranded RNA at G residues
EnzymeRNase T1
FormatBulk Magnetic SMART Digest Resin
For Use With (Application)Oligonucleotide Mapping
Product LineSMART Digest
TypeRNA Digestion
IncludesBulk Magnetic SMART Digest Resin, SMART Digest Buffer
Unit SizeEach
Showing 2 of 2

These RNase kits use optimized, heat stable enzymes on magnetic beads, allowing for control of partial digestion to produce required fragments of ideal length for sequencing by HRAM-MS.

Easy and Simple

  • A simple process and control of digestion time ensure required fragment length for comprehensive mRNA sequencing by HRAM-MS
  • Easily automate the entire protocol for high-throughput processing
  • Single nuclease digestion allows full characterization of mRNA

Reliable Results

  • Increased reproducibility over existing protocols
  • Higher data confidence
  • No nuclease contamination of the analytical column


RNase kits are available with with two endoribonuclease enzyme specificities:

  • RNase T1 degrades single-stranded RNA at G residues
  • RNase A degrades single-stranded RNA at C and U residues

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