CaptureSelect™ Human IgG-Fc PK Biotin Conjugate consists of a 13 kDa llama antibody fragment (affinity ligand) that specifically binds to the Fc part of all four human IgG subclasses without cross-binding to mouse, rat, rhesus, and cynomolgus monkey IgG. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.
The CaptureSelect™ Human IgG-Fc PK Biotin Conjugate allows you to:
• Detect, quantitate, and characterize all human IgG antibodies (subclasses 1 to 4), recombinant human IgG antibodies, human IgG-derived Fc-fusion proteins in, for instance, non-human plasma and/or serum samples like mouse, rat , rhesus, and cynomolgus monkey, thereby making it extremely suitable for setting up pharmacokinetics (PK) assays
Applications for CaptureSelect™ Human IgG-Fc PK Biotin Conjugate include ELISA, Western blot, Gyrolab™-based immunoassays, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).
For Research Use Only. Not for use in diagnostic procedures.