Thermo Scientific Chemicals

2-(Chloromethyl)pyridine hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: A10226.22
100 g, Each
Thermo Scientific Chemicals

2-(Chloromethyl)pyridine hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: A10226.22
100 g, Each
Quantity
Catalog number: A10226.22
also known as A10226-22
Price (USD)
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Chemical Identifiers

CAS
6959-47-3
IUPAC Name
hydrogen 2-(chloromethyl)pyridine chloride
Molecular Formula
C6H7Cl2N
InChI Key
JPMRGPPMXHGKRO-UHFFFAOYSA-N
SMILES
[H+].[Cl-].ClCC1=CC=CC=N1
Assay (Titration ex Chloride)
≥97.5 to ≤102.5%
Water Content (Karl Fischer Titration)
≤2.5%
Solution Test
0.5g in 20ml Ethanol to be transparent or almost transparent
Appearance (Color)
White to yellow or pale brown
Form
Crystals or powder or crystalline powder

Description

2-(Chloromethyl)pyridine hydrochloride was used as reagent in base catalyzed alkylation of p-tert-butylcalix[6]arene and p-tert-butylcalix[5]arene in DMF. It was used in the synthesis of Gd3+ diethylenetriaminepentaacetic acid bisamide complex, a Zn2+-sensitive magnetic resonance imaging contrast agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(Chloromethyl)pyridine hydrochloride was used as reagent in base catalyzed alkylation of p-tert-butylcalix[6]arene and p-tert-butylcalix[5]arene in DMF. It was used in the synthesis of Gd3+ diethylenetriaminepentaacetic acid bisamide complex, a Zn2+-sensitive magnetic resonance imaging contrast agent.

Solubility
Soluble in water, acetone (10-50mg/ml), 95%ethanol (100mg/ml).

Notes
Hygroscopic store in inert gas Store away from strong oxidizing agents. keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

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