1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%
1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%
1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%
1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%
Thermo Scientific Chemicals

1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%

CAS: 328-73-4 | C8H3F6I | 340.007 g/mol
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25 g
Catalog number A10878.06
also known as A10878-06
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Each
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Chemical Identifiers
CAS328-73-4
IUPAC Name1-iodo-3,5-bis(trifluoromethyl)benzene
Molecular FormulaC8H3F6I
InChI KeyVDPIZIZDKPFXLI-UHFFFAOYSA-N
SMILESFC(F)(F)C1=CC(=CC(I)=C1)C(F)(F)F
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to yellow
Assay (GC)≥97.0%
Refractive Index1.4620-1.4670 @ 20?C
FormLiquid
3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.

Solubility
Slightly soluble in water.

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.
RUO – Research Use Only

General References:

  1. Hiroshi Nishida,; Naoko Takada,; Masaji Yoshimura,; Takaaki Sonoda,; Hiroshi Kobayashi. Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Highly Lipophilic Stable Anionic Agent for Solvent-extraction of Cations . Bulletin of the Chemical Society of Japane. 1984, 57 (9), pg no.
  2. Simon M. E. Simpkins,; Michael D. Weller,; Liam R. Cox. β-Chlorovinylsilanes as masked alkynes in oligoyne assembly: synthesis of the first aryl-end-capped dodecayne. Chem. Commun. 2007, 39, 4035-4037.