3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.
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Applications
3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.
Solubility
Slightly soluble in water.
Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.
RUO – Research Use Only
General References:
- Hiroshi Nishida,; Naoko Takada,; Masaji Yoshimura,; Takaaki Sonoda,; Hiroshi Kobayashi. Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate. Highly Lipophilic Stable Anionic Agent for Solvent-extraction of Cations . Bulletin of the Chemical Society of Japane. 1984, 57 (9), pg no.
- Simon M. E. Simpkins,; Michael D. Weller,; Liam R. Cox. β-Chlorovinylsilanes as masked alkynes in oligoyne assembly: synthesis of the first aryl-end-capped dodecayne. Chem. Commun. 2007, 39, 4035-4037.