2,6-Dichloropyrazine, 98%
2,6-Dichloropyrazine, 98%
2,6-Dichloropyrazine, 98%
Thermo Scientific Chemicals

2,6-Dichloropyrazine, 98%

CAS: 4774-14-5 | C4H2Cl2N2 | 148.974 g/mol
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25 g
Catalog number A11175.06
also known as A11175-06
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5 g
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Price (USD)
115.65
Online Exclusive
128.00
Save 12.35 (10%)
Each
Chemical Identifiers
CAS4774-14-5
IUPAC Name2,6-dichloropyrazine
Molecular FormulaC4H2Cl2N2
InChI KeyLSEAAPGIZCDEEH-UHFFFAOYSA-N
SMILESClC1=CN=CC(Cl)=N1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to cream to pale yellow to pale brown
Assay (GC)≥97.5%
FormCrystals or powder or crystalline powder
Melting Point (clear melt)51-56?C
2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.

Solubility
Soluble in ethanol and methanol.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong acids and bases.
RUO – Research Use Only

General References:

  1. Zhao, M.; Li, P.; Xie, X.; Su, J.; Zheng, W. Synthesis and structural characterization of 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyridine zinc and 2,6-bis(1,2,4-diazaphospholyl-1-yl)pyrazine copper complexes. Polyhedron 2015, 85, 302-311.
  2. Tominaga, M.; Kunitomi, N.; Katagiri, K.; Itoh, T. Adamantane-Based Oxacyclophanes Containing Pyrazines: Synthesis, Crystal Structure, and Self-Assembly Behavior. Org. Lett. 2015, 17 (4), 786-789.