2-Aminothiazole, 97%
2-Aminothiazole, 97%
2-Aminothiazole, 97%
2-Aminothiazole, 97%
Thermo Scientific Chemicals

2-Aminothiazole, 97%

CAS: 96-50-4 | C3H4N2S | 100.14 g/mol
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Catalog number A12026.36
also known as A12026-36
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Chemical Identifiers
CAS96-50-4
IUPAC Name1,3-thiazol-2-amine
Molecular FormulaC3H4N2S
InChI KeyRAIPHJJURHTUIC-UHFFFAOYSA-N
SMILESNC1=NC=CS1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Cream to dark brown to brown
FormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥96.0 to ≤104.0%
Assay (GC)≥96.0%
Identification (FTIR)Conforms
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2-Aminothiazole is used in the synthesis of 2-aminothiazole-modified silica gel and also used in Ulmann coupling with 2-chlorobenzoic acids mediated by ultrasonic irradiation. It acts as a component of disperse dye, thyroid inhibitor in the treatment of hyperthyroidism, as the acid tartrate and as a therapeutic drug for prion diseases. It is also used to kill bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, alcohol and ether.

Notes
Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, nitric acid and sulfuric acid.
RUO – Research Use Only

General References:

  1. Yadav, P.; Dutta, P. K.; Ballabh, A. Combinatorial Library Approach to Realize 2-Aminothiazole-Based Two-Component Hydrogelator: A Structure-Property Correlation.Cryst. Growth Des. 2014, 14 (11), 5966-5975.
  2. Xiong, C.; Zhou, S.; Liu, X.; Jia, Q.; Ma, C.; Zheng, X. 2-Aminothiazole Functionalized Polystyrene for Selective Removal of Au(III) in Aqueous Solutions. Ind. Eng. Chem. Res. 2014, 53 (6), 2441-2448.
  3. Xiong, C.; Jia, Q.; Chen, X.; Wang, G.; Yao, C. Optimization of Polyacrylonitrile-2-aminothiazole Resin Synthesis, Characterization, and Its Adsorption Performance and Mechanism for Removal of Hg(II) from Aqueous Solutions. Ind. Eng. Chem. Res. 2013, 52 (14), 4978-4986.
  4. Giles, K.; Berry, D. B.; Condello, C.; Hawley, R. C.; Gallardo-Godoy, A.; Bryant, C.; Oehler, A.; Elepano, M.; Bhardwaj, S.; Patel, S.; Silber, M.; Guan, S.; Armond, S. J.; Renslo, A. R.; Prusiner, S. B. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J. Pharmacol. Exp. Ther. 2015, 355 (1), 2-12.