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3,4-Diaminopyridine, 97%
CAS: 54-96-6 | C5H7N3 | 109.132 g/mol
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Catalog number A12465.14
also known as A12465-14
Price (USD)
484.65
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Ends: 28-Dec-2026
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Quantity:
25 g
Price (USD)
484.65
Special offer
Online exclusive
Ends: 28-Dec-2026
570.00Save 85.35
Each
Chemical Identifiers
CAS54-96-6
IUPAC Namepyridine-3,4-diamine
Molecular FormulaC5H7N3
InChI KeyOYTKINVCDFNREN-UHFFFAOYSA-N
SMILESNC1=CC=NC=C1N
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to grey or yellow to brown
FormCrystals or powder or crystalline powder
Assay (HPLC)≥96.0%
CommentMay darken on storage
Water Content (Karl Fischer Titration)≤1.50%
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It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.
Solubility
Soluble in water (24 mg/ml at 20°C), alcohol. Slightly soluble in ether.
Notes
Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.
It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.
Solubility
Soluble in water (24 mg/ml at 20°C), alcohol. Slightly soluble in ether.
Notes
Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- J. M. Rubin-Preminger.; U. Englert. 3,4-Diaminopyridine Acta Cryst. 2007, 63 (2),o757-o758 .
- Jorge Molgó.; H→kan Lundh.; Stephen Thesleff. Potency of 3,4-Diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes. Eur. J. Pharmacol. 1980, 61 (1),25-34.