N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
Thermo Scientific Chemicals

N,N-Dimethyl-n-octylamine, 95%

CAS: 7378-99-6 | C10H23N | 157.30 g/mol
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Catalog number A12546.09
also known as A12546-09
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Price (USD)
38.65
Online Exclusive
42.70
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Each
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Chemical Identifiers
CAS7378-99-6
IUPAC Namedimethyl(octyl)amine
Molecular FormulaC10H23N
InChI KeyUQKAOOAFEFCDGT-UHFFFAOYSA-N
SMILESCCCCCCCCN(C)C
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SpecificationsSpecification SheetSpecification Sheet
Refractive Index1.4220-1.4270 @ 20?C
Appearance (Color)Clear to slightly hazy colorless
FormLiquid
Assay from Supplier's CofA≥94.0% (sum of C8 isomers/chains)
CommentHazyness may settle to a white sediment on standing.
N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

Solubility
Slightly miscible with water.

Notes
Air sensitive. Incompatible with strong oxidizing agents, strong acids and copper.
RUO – Research Use Only

General References:

  1. Modifier for reverse-phase liquid chromatographic separation of amines.
  2. Matsukizono, H.; Endo, T. Synthesis of polyhydroxyurethanes from di(trimethylolpropane) and their application to quaternary ammonium chloride-functionalized films. RSC Adv. 2015, 5 (87), 71360-71369.
  3. Matsunaga, H.; Haginaka, J. Separation of enantiomers on chiral stationary phase based on chicken alpha 1-acid glycoprotein: Effect of silica particle diameters on column performance. J. Chromatogr. A 2014, 1363, 96-100.