Methyl 3-aminothiophene-2-carboxylate is used in the synthesis of 4-nitro and 4-aminothienyl ureas, total synthesis of quinazolinocarboline alkaloids and in preparation of thienopyrimidinone analogs.
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Applications
Methyl 3-aminothiophene-2-carboxylate is used in the synthesis of 4-nitro and 4-aminothienyl ureas, total synthesis of quinazolinocarboline alkaloids and in preparation of thienopyrimidinone analogs.
Solubility
Slightly soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only
General References:
- John M. Barkera.; Patrick R. Huddlestona.; Michael L. An Easy Synthesis of 3-Amino- and 3-Nitrothiophene. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1995, 25 (23), 3729-3734.
- Wu Yun Ren.; Mu Ill Lim.; Brian A. Otter.; Robert S. Klein. Synthetic studies of the thieno[3,2-d]pyrimidine C-nucleoside isostere of inosine. J. Org. Chem. 1982, 47 (24), 4633-4637.