Methyl 3-aminothiophene-2-carboxylate, 98+%
Methyl 3-aminothiophene-2-carboxylate, 98+%
Methyl 3-aminothiophene-2-carboxylate, 98+%
Thermo Scientific Chemicals

Methyl 3-aminothiophene-2-carboxylate, 98+%

CAS: 22288-78-4 | C6H7NO2S | 157.19 g/mol
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Catalog number A12802.06
also known as A12802-06
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Price (USD)
37.65
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41.90
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Each
Chemical Identifiers
CAS22288-78-4
IUPAC Namemethyl 3-aminothiophene-2-carboxylate
Molecular FormulaC6H7NO2S
InChI KeyTWEQNZZOOFKOER-UHFFFAOYSA-N
SMILESCOC(=O)C1=C(N)C=CS1
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SpecificationsSpecification SheetSpecification Sheet
Assay (Non-aqueous acid-base Titration)≥98.0 to ≤102.0%
FormCrystals or powder or crystalline powder
Appearance (Color)Cream to pale brown
Melting Point (clear melt)63.0-69.0?C
Methyl 3-aminothiophene-2-carboxylate is used in the synthesis of 4-nitro and 4-aminothienyl ureas, total synthesis of quinazolinocarboline alkaloids and in preparation of thienopyrimidinone analogs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl 3-aminothiophene-2-carboxylate is used in the synthesis of 4-nitro and 4-aminothienyl ureas, total synthesis of quinazolinocarboline alkaloids and in preparation of thienopyrimidinone analogs.

Solubility
Slightly soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only

General References:

  1. John M. Barkera.; Patrick R. Huddlestona.; Michael L. An Easy Synthesis of 3-Amino- and 3-Nitrothiophene. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1995, 25 (23), 3729-3734.
  2. Wu Yun Ren.; Mu Ill Lim.; Brian A. Otter.; Robert S. Klein. Synthetic studies of the thieno[3,2-d]pyrimidine C-nucleoside isostere of inosine. J. Org. Chem. 1982, 47 (24), 4633-4637.