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N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%
CAS: 24589-78-4 | C6H12F3NOSi | 199.25 g/mol
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Catalog number A13141.14
also known as A13141-14
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202.65
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Quantity:
25 g
Price (USD)
202.65
Online Exclusive
225.00Save 22.35 (10%)
Each
Chemical Identifiers
CAS24589-78-4
IUPAC Name2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)acetamide
Molecular FormulaC6H12F3NOSi
InChI KeyMSPCIZMDDUQPGJ-UHFFFAOYSA-N
SMILESCN(C(=O)C(F)(F)F)[Si](C)(C)C
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Specifications
Specification Sheet
Specification SheetFormLiquid
Appearance (Color)Clear colorless
Assay (GC)≥96.0%
Identification (FTIR)Conforms
Refractive Index1.3775-1.3825 @ 20?C
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Solubility
Immiscible with water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Solubility
Immiscible with water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
General References:
- Powerful silylating agent for a wide range of functional groups: J. Chromat., 115, 591 (1975); 134, 387 (1977); Chromatographia, 9, 440 (1976). See Appendix 4.
- Cabanelas, D. G.; Wright, L. P.; Paetz, C.; Onkokesung, N.; Gershenzon, J.; Concepción, M. R.; Phillips, M. A. The diversion of 2-C-methyl-d-erythritol-2, 4-cyclodiphosphate from the 2-C-methyl-d-erythritol 4-phosphate pathway to hemiterpene glycosides mediates stress responses in Arabidopsis thaliana. Plant J. 2015, 82 (1), 122-137.
- Wong, A. S. Y.; Ho, E. N. M.; Wan, T. S. M.; Lam, K. K. H.; Stewart, B. D. Metabolic studies of oxyguno in horses. Anal. Chim. Acta 2015, 891, 190-202.