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Colchicine, 95% (dry wt.)
Colchicine, 95% (dry wt.)
Colchicine, 95% (dry wt.)
Thermo Scientific Chemicals

Colchicine, 95% (dry wt.)

CAS: 64-86-8 | C22H25NO6 | 399.44 g/mol
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25 g
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Catalog number A13240.06
also known as A13240-06
Price (USD)
360.65
Online Exclusive
400.00
Save 39.35 (10%)
Each
Quantity:
5 g
Request bulk or custom format
Price (USD)
360.65
Online Exclusive
400.00
Save 39.35 (10%)
Each
Chemical Identifiers
CAS64-86-8
IUPAC NameN-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0²,⁷]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
Molecular FormulaC22H25NO6
InChI KeyIAKHMKGGTNLKSZ-INIZCTEOSA-N
SMILESCOC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
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SpecificationsSpecification SheetSpecification Sheet
Identification (FTIR)Conforms
Assay (HPLC)≥94.0% (dry wt. basis)
Loss on Drying≤3.5% (105°C/constant weight)
Appearance (Color)White to pale cream to pale yellow
FormPowder

Colchicine is used as an anti-inflammatory agent for long-term treatment of behcet's Disease. It is used for constipation-predominant irritable bowel syndrome in women, and for treatment of severe or persistent aphthous stomatitis (canker sores).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water and alcohol. Sparingly soluble in ether.

Notes
Incompatible with strong oxidizing agents and mineral acids.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Hwang, D.; Wang, J.; Li, W.; Miller, D. D. Structural Optimization of Indole Derivatives Acting at Colchicine Binding Site as Potential Anticancer Agents. ACS Med. Chem. Lett. 2015, 6 (9), 993-997.
  2. Kuroiwa, K.; Ishii, H.; Matsuno, K.; Asai, A.; Suzuki, Y. Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents. ACS Med. Chem. Lett. 2015, 6 (3), 287-291.