1-Phenyl-1H-pyrazole is used in the preparation of 4,5-diphenylpyrazolo[1,5-a]quinoline, 1-(1,2,3,4-tetraphenylnaphthalen-5-yl)pyrazole and 1-(1,2,3,4,5,6,7,8-octaphenylanthracen-9-yl)pyrazole. It acts as a cyclometallated ligand in the preparation of new heteroleptic iridium(III) complexes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Phenyl-1H-pyrazole is used in the preparation of 4,5-diphenylpyrazolo[1,5-a]quinoline, 1-(1,2,3,4-tetraphenylnaphthalen-5-yl)pyrazole and 1-(1,2,3,4,5,6,7,8-octaphenylanthracen-9-yl)pyrazole. It acts as a cyclometallated ligand in the preparation of new heteroleptic iridium(III) complexes.
Solubility
Soluble in water.
Notes
Store away from oxidizing agents. Store in a cool, dry conditions in a well sealed container.
RUO – Research Use Only
General References:
- Nobuyoshi Umeda; Koji Hirano; Tetsuya Satoh; Naoto Shibata; Hirofumi Sato; Masahiro Miura. Rhodium-catalyzed oxidative 1:1, 1:2, and 1:4 coupling reactions of phenylazoles with internal alkynes through the regioselective cleavages of multiple C-H bonds. Journal of Organic Chemistry.2011, 76 (1), 13-24.
- Indira Fabre; Niklas von Wolff; Gaëtan Le Duc; Emmanuel Ferrer Flegeau; Christian Bruneau; Pierre H Dixneuf; Anny Jutand. Autocatalytic intermolecular versus intramolecular deprotonation in C-H bond activation of functionalized arenes by ruthenium(II) or palladium(II) complexes. Chemistry: A European Journal.2013, 19 (23), 7595-7604.