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Thermo Scientific™
Thiophene-3-carboxaldehyde, 96%
CAS: 498-62-4 | C5H4OS | 112.146 g/mol
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Catalog number A14628.09
also known as A14628-09
Price (USD)
101.00
Each
Quantity:
10 g
Price (USD)
101.00
Each
Chemical Identifiers
CAS498-62-4
IUPAC Namethiophene-3-carbaldehyde
Molecular FormulaC5H4OS
InChI KeyRBIGKSZIQCTIJF-UHFFFAOYSA-N
SMILESO=CC1=CSC=C1
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Specifications
Specification Sheet
Specification SheetAssay from Supplier's CofA≥95.0% (US sourced material, GC)
CommentMaterial sourced in UK and US
FormLiquid
Assay (GC)≥95.0% (UK sourced material)
Free acid (titration)≤2.0% (UK sourced material)
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Thiophene-3-carboxaldehyde has been used in the synthesis of series of 4-substituted 2-thiophenesulfonamides, acetal and ketal derivatives of 4?-demethylepipodophyllotoxin-β-D-glucoside and epipodophyllotoxin-β-D-glucoside. Also has been used to produce 1,2-di-3-thienyl-2-hydroxyethanone (3,3?-thenoin), 3-thienyl symmetric analog of benzoin.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Thiophene-3-carboxaldehyde has been used in the synthesis of series of 4-substituted 2-thiophenesulfonamides, acetal and ketal derivatives of 4′-demethylepipodophyllotoxin-β-D-glucoside and epipodophyllotoxin-β-D-glucoside. Also has been used to produce 1,2-di-3-thienyl-2-hydroxyethanone (3,3′-thenoin), 3-thienyl symmetric analog of benzoin.
Solubility
Not miscible in water.
Notes
It is sensitive to air. Incompatible with oxidizing agents and heat.
Thiophene-3-carboxaldehyde has been used in the synthesis of series of 4-substituted 2-thiophenesulfonamides, acetal and ketal derivatives of 4′-demethylepipodophyllotoxin-β-D-glucoside and epipodophyllotoxin-β-D-glucoside. Also has been used to produce 1,2-di-3-thienyl-2-hydroxyethanone (3,3′-thenoin), 3-thienyl symmetric analog of benzoin.
Solubility
Not miscible in water.
Notes
It is sensitive to air. Incompatible with oxidizing agents and heat.
RUO – Research Use Only
General References:
- J.M.Holmes; G.C.Lee; M.Wijono; R.Weinkam; L.A.Wheeler; M.E.Garst. Synthesis and carbonic anhydrase inhibitory activity of 4-substituted 2-thiophenesulfonamides. Journal of Medicinal Chemistry. 1994, 37, (11),1646-1651
- R.S.Gupta; P.C.Chenchaiah; R.Gupta. Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities. Anti-cancer drug design. 1987, 2, (1),1-12