Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Phenylhydrazine hydrochloride, 99%
Thermo Scientific Chemicals

Phenylhydrazine hydrochloride, 99%

CAS: 59-88-1 | C6H9ClN2 | 144.60 g/mol
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Catalog NumberQuantity
A14645.22100 g
Catalog number A14645.22
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Chemical Identifiers
CAS59-88-1
IUPAC Namehydrogen phenylhydrazine chloride
Molecular FormulaC6H9ClN2
InChI KeyJOVOSQBPPZZESK-UHFFFAOYSA-N
SMILES[H+].[Cl-].NNC1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
Identification (FTIR)Conforms
Assay (Titration ex Chloride)≥98.5 to ≤101.5%
Appearance (Color)White to cream
FormCrystals or powder or crystalline powder
Assay (HPLC)>98.5%
Phenylhydrazine hydrochloride is used as a selective mannosidase inhibitor. It is used in the study of tyrosine phosphorylation of janus protein tyrosine kinase in the EPO-responsive normal erythroblastoid cells of anemic mice. It is used in steroid assays and as an N-protecting reagent. Its free base, phenylhydrazine is used to prepare indoles, which find application as intermediates in the synthesis of various dyes and pharmaceuticals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenylhydrazine hydrochloride is used as a selective mannosidase inhibitor. It is used in the study of tyrosine phosphorylation of janus protein tyrosine kinase in the EPO-responsive normal erythroblastoid cells of anemic mice. It i
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Butin, A. V.; Uchuskin, M. G.; Pilipenko, A. S.; Serdyuk, O. V.; Trushkov, I. V. Unusual reactivity of beta-(3-indolyl)-alpha, beta-unsaturated ketones. 2-Acetylvinyl group removal by phenylhydrazine hydrochloride. Tetrahedron Lett. 2011, 52 (41), 5255-5258.
  2. Muralirajan, K.; Haridharan, R.; Prakash, S.; Cheng, C. H. Rhodium(III)-Catalyzed in situ Oxidizing Directing Group-Assisted C H Bond Activation and Olefination: A Route to 2-Vinylanilines. Adv. Synth. Catal. 2015, 357, (4), 761-766.