2'-Fluoroacetophenone, 97%
2'-Fluoroacetophenone, 97%
2'-Fluoroacetophenone, 97%
Thermo Scientific Chemicals

2'-Fluoroacetophenone, 97%

CAS: 445-27-2 | C8H7FO | 138.141 g/mol
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Catalog number A15128.06
also known as A15128-06
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Price (USD)
37.65
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42.20
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Chemical Identifiers
CAS445-27-2
IUPAC Name1-(2-fluorophenyl)ethan-1-one
Molecular FormulaC8H7FO
InChI KeyQMATYTFXDIWACW-UHFFFAOYSA-N
SMILESCC(=O)C1=CC=CC=C1F
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless
FormLiquid
Refractive Index1.5060-1.5110 @ 20?C
Assay (GC)≥96.0%
Identification (FTIR)Conforms
2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2′-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

Solubility
Soluble in Acetone, Chloroform, Dichloromethane, Ethanol, Ethyl Acetate and Methanol.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Christine E Garrett.; Kapa Prasad.; Oljan Repic.; Thomas J Blacklock. The enantioselective reduction of 2'-fluoroacetophenone utilizing a simplified CBS-reduction procedure. Tetrahedron: Asymmetry. 2009, 13, (13), 1347-1349.