Uracil, 99+%
Uracil, 99+%
Uracil, 99+%
Thermo Scientific Chemicals

Uracil, 99+%

CAS: 66-22-8 | C4H4N2O2 | 112.09 g/mol
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Catalog number A15570.0B
also known as A15570-0B
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419.65
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1000 g
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Price (USD)
419.65
Online Exclusive
466.00
Save 46.35 (10%)
Each
Chemical Identifiers
CAS66-22-8
IUPAC Name1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular FormulaC4H4N2O2
InChI KeyISAKRJDGNUQOIC-UHFFFAOYSA-N
SMILESO=C1NC=CC(=O)N1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White
FormPowder
Identification (FTIR)Conforms
Assay (HPLC)≥99.0%
Melting Point>300?C
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

Applications
Uracil is produced by hydrolysis of nucleic acid and used in biochemical research. It serves as a allosteric regulator and coenzyme for reactions in the human body and in plants. It reacts with fluorine to get 5-fluorouracil, which is an anticancer drug. Further, it is used in drug delivery and in pharmaceuticals. In addition to this, it is used in the synthesis of caffeine and in the determination of microbial contamination of tomatoes.

Solubility
Soluble in water, aqueous ammonia, 1M sodium hydroxide solution and alkalies. Insoluble in ethanol and ether.

Notes
Incompatible with water, air and strong oxidizing agents.
RUO – Research Use Only

General References:

  1. For a review of the use of uracils as starting materials in heterocyclic synthesis, see: Adv. Het. Chem., 55, 130 (1992).
  2. Fornaro, T.; Burini, D.; Biczysko, M.; Barone, V. Hydrogen-Bonding Effects on Infrared Spectra from Anharmonic Computations: Uracil-Water Complexes and Uracil Dimers. J. Phys. Chem. A 2015, 119 (18), 4224-4236.
  3. Cavaleiro, A. M.; Kim, S. H.; Seppala, S.; Nielsen, M. T.; Nørholm, M. H. Accurate DNA assembly and genome engineering with optimized uracil excision cloning. ACS Synth. Biol. 2015, 4 (9), 1042-1046.