NEWS: Bone Marrow MSCs isolated under hypoxia have been used in a Phase 2 clinical trial for cardiovascular disease sponsored by Stemedica Cell Technologies, Inc. See article and clinical trial.

StemPro® BM Mesenchymal Stem Cells

Catalog number: A15652

Gibco™  Related applications: Stem Cell Culture

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Description

StemPro® BM Mesenchymal Stem Cells are cryopreserved human bone marrow mesenchymal stem cells (BM MSCs). These Off-the-Shelf cells are manufactured to meet Good Manufacturing Practice (GMP) manufacturing standards in a California-licensed facility and available for Research Use Only. They are isolated and expanded in culture to passage 4 under a low oxygen (ischemia tolerant (it)) proprietary clinical-scale manufacturing process using Bovine Growth Serum (BGS)-supplemented media and cryopreserved in an animal origin free cryopreservation medium. The cells are supplied at 1x106 and 5x106 viable cells/vial. A Certificate of Analysis is available for each lot which documents the quality control specifications, test results and donor information.

StemPro® BM Mesenchymal Stem Cells allow you to:

• Minimize assay variability with itMSCs manufactured in compliance with GMP manufacturing standards
• Improve functionality studies with immature, high potency MSCs
• No observed tumorigenicity and toxicity in GLP-compliant animal studies
• Accommodate experiments requiring one large lot of MSCs
• Minimize your chance of assay failure when using tested cells, reagents and protocols

Immature, High Potency, Low Oxygen-Cultured MSCs
StemPro® BM Mesenchymal Stem Cells are derived from human bone marrow aspirates from qualified, traceable donors. The cells are isolated, cultured and expanded in compliance with GMP manufacturing standards in a California-licensed facility using a proprietary clinical-scale Reduced Oxygen Tension manufacturing process. Cells manufactured in reduced oxygen tension environments result in higher cell yields of highly potent immature stem cells compared to cells expanded in normal oxygen culture conditions.

Proven Non-toxic Profiles
Cells have demonstrated to be non-toxic and non-tumorigenic in GLP animal studies, which were performed according to FDA guidelines.

A large lot can be made available for those requiring assay standardization. Protocols using tested reagents will be provided to help minimize your chance of assay failure when using reagents and cells that have not been evaluated to work together. View our tested media and reagents.

High Post-Cryopreservation Viability
StemPro® Mesenchymal Stem Cells are supplied in CryoStor® cryopreservation medium at 1x106 and 5x106 viable cells/vial. This medium is animal origin free and shown to support high cell viabilities post-thawing. Controlled processes are used for cryopreservation, handling and shipping to help minimize risk of adverse effects to the quality of the cells.

Made in USA by Stemedica for Thermo Fisher Scientific.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Age: Adult
Cell Passage Number: Passage 4
Cell Type: Stem Cells (Mesenchymal)
Culture Type: Adherent Cell Culture
Donor Attributes: Normal
Form: Cryopreserved
Media Recommendation: Serum-Supplemented or Serum-Free Media
Product Size: 1 x 106 cells
Species: Human

Contents & storage

1 vial. Remove from foil pouch and store in liquid nitrogen.

Documents

Manuals & protocols

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