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Thermo Scientific Chemicals
Aurintricarboxylic acid
CAS: 4431-00-9 | C22H14O9 | 422.345 g/mol
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Catalog number A15905.14
also known as A15905-14
Price (USD)
168.00
Each
Quantity:
25 g
Price (USD)
168.00
Each
Chemical Identifiers
CAS4431-00-9
IUPAC Name5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxocyclohexa-2,5-dien-1-yl)methyl]-2-hydroxybenzoic acid
Molecular FormulaC22H16O9
InChI KeyYETAHXYTPZCNBG-UHFFFAOYNA-N
SMILESOC(=O)C1=CC(C=CC1=O)C(C1=CC=C(O)C(=C1)C(O)=O)C1=CC=C(O)C(=C1)C(O)=O
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Specifications
Specification Sheet
Specification SheetFormPowder or crystalline powder
CommentSuitable for the estimation of aluminium
Identification (FTIR)Conforms
Appearance (Color)Dark red
Assay (Aqueous acid-base Titration)≥90%
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents.
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents.
RUO – Research Use Only
General References:
- Richard B. Hallick.; Barry K. Chelm.; Patrick W. Gray.; Emil M. Orozco Jr. Use of aurintricarboxylic acid as an inhibitor of nucleases during nucleic acid isolation. Nucl. Acids Res. 1979, 4 (9),3055-3064.
- Jill M. Roberts-Lewis.; Val R. Marcy.; Yonghua Zhao.; Jeffry L. Vaught.; Robert Siman.; Michael E. Lewis. Aurintricarboxylic Acid Protects Hippocampal Neurons from NMDA-and Ischemia-Induced Toxicity In Vivo. Journal of Neurochemistry. 1993, 61 (1), 378-381.