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Thermo Scientific Chemicals

Rose Bengal

Name: Rose Bengal
SKU: A17053.36
Price: 616.65 USD

CAS: 632-69-9 | C20H4Cl4I4Na2O5 | 1019.644 g/mol

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Catalog number A17053.36

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500 g

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Price (USD)

616.65

Online Exclusive

685.00

Save 68.35 (10%)

Each

Chemical Identifiers

CAS632-69-9

IUPAC Namedisodium 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-3',6'-bis(olate)

Molecular FormulaC20H2Cl4I4Na2O5

InChI KeyKCQREHTWEUECQT-UHFFFAOYSA-L

SMILES[Na+].[Na+].[O-]C1=C(I)C=C2C(OC3=C(I)C([O-])=C(I)C=C3C22OC(=O)C3=C(Cl)C(Cl)=C(Cl)C(Cl)=C23)=C1I

Specifications

Specification Sheet

Solution Test0.1 wt.% in water (+ 1ml 1% Na₂CO₃): Clear

lambda-max (UV-Vis)540-550nm (in water)

Specific Absorbance (E 1%/1cm)(at |l max) : ≥600

Appearance (Color)Red to dark red to brown

FormPowder

Rose Bengal is a stain used in the eye drops to identify the eye damage. It finds application in the preparation of foraminifera for microscopic analysis, photosensitizing reactions and as a dye. In synthetic chemistry, it is utilized to convert triplet oxygen to singlet oxygen, which is used in [2+2] cycloadditions with alkenes. Its derivatives have important medical functions and used for the treatment of cancer. It acts as an alternative to phloxine B in Kreyberg's stain for keratin and mucus. As a fluorescent probe, it is used for the determination of NAD binding sites of alcohol dehydrogenase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Yuan, K.; Wang, J.; Zhai, H.; Chen, Z.; Huang, L.; Su, Z. Sensitive determination of rose bengal in brown sugar by a molecularly imprinted solid-phase extraction monolithic capillary column coupled with capillary electrophoresis. Anal. Methods 2015, 7 (19), 8297-8303.
Lee, J. S.; Lee, B. I.; Park, C. B. Photo-induced inhibition of Alzheimer's beta-amyloid aggregation in vitro by rose bengal. Biomater. 2015, 38, 43-49.