Phenolphthalein, 98%
Phenolphthalein, 98%
Phenolphthalein, 98%
Thermo Scientific Chemicals

Phenolphthalein, 98%

CAS: 77-09-8 | C20H14O4 | 318.33 g/mol
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Catalog number A17135.18
also known as A17135-18
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Chemical Identifiers
CAS77-09-8
IUPAC Name3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one
Molecular FormulaC20H14O4
InChI KeyKJFMBFZCATUALV-UHFFFAOYSA-N
SMILESOC1=CC=C(C=C1)C1(OC(=O)C2=CC=CC=C12)C1=CC=C(O)C=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to cream
Assay (HPLC)≥97.5%
Color ChangeColorless to pink @ pH 8.2
Identification (FTIR)Conforms
lambda-max (UV-Vis)550-555nm (0.1M NaOH)
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Phenolphthalein is widely used as an indicator in acid-base titrations, water treatment applications. Due to its pH sensitivity, It is used to the check extent of carbonation in concrete, soap and in toys as diapering work. It is used in Kastle-Meyer test, which identifies the substances containing blood.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenolphthalein is widely used as an indicator in acid-base titrations, water treatment applications. Due to its pH sensitivity, It is used to the check extent of carbonation in concrete, soap and in toys as diapering work. It is used in Kastle-Meyer test, which identifies the substances containing blood.

Solubility
Soluble in alcohol. Slightly soluble in dimethyl sulfoxide and insoluble in benzene or hexane.

Notes
Acid-base indicator: pH 8.0 - 10.0.Incompatible with strong oxidizing agents.
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Acid-base indicator: pH 8.0 - 10.0.
  2. Dobrydneva, Y.; Wilson, E.; Abelt, C. J.; Blackmore, P. F. Phenolphthalein as a Prototype Drug for a Group of Structurally Related Calcium Channel Blockers in Human Platelets. J. Cardiovasc. Pharmacol. 2009, 53 (3), 231-240.
  3. Vishwakarma, N. K.; Patel, V. K.; Hira, S. K.; Ramesh, K.; Srivastava, P.; Mitra, K.; Singh, S.; Chattopadhyay, D.; Maiti, P.; Misra, N.; Manna, P. P.; Ray, B. Tadpole-shaped Beta-cyclodextrin-tagged poly(N-vinylpyrrolidone): synthesis, characterization and studies of its complexation with phenolphthalein and anti tumor activities. RSC Adv. 2015, 5 (20), 15547-15558.