It is employed in biological research purpose. Benzyl bromoacetate was used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is employed in biological research purpose. Benzyl bromoacetate was used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.
Solubility
Not miscible or difficult to mix in water.
Notes
Store away from oxidizing agents and strong bases. Keep the container tightly closed in a cool, dry place. Store under 20˚C Freezer, Under Inert Atmosphere.
RUO – Research Use Only
General References:
- Herrin TR.; Fairgrieve JS.; Bower RR.; Shipkowitz NL. Synthesis and anti-herpes simplex activity of analogues of phosphonoacetic acid.J Med Chem.1977,20(5), 660-663.
- Feagin TA.; Shah N.; Heemstra JM. Micellar. Convenient and scalable synthesis of fmoc-protected Peptide nucleic Acid backbone.J Nucleic Acids.2012,2012.
- Toru Masaka.; Takuya Matsuda.; Yingpeng Li.; Yuki Koide.; Akira Takami.; Kenji Yano.; Ryosuke Imai.; Risa Ichihara.; Nobuhiro Yagi.; Hideharu Suzuki.; Hidemasa Hikawa.; Katsuhide Terada.; Yuusaku Yokoyama. Synthesis of VIP-lipopeptide using a new linker to modify liposomes: towards the development of a drug delivery system for active targeting.Chem Pharm Bull (Tokyo).2013,61(11), 1184-7.