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Thermo Scientific Chemicals
2,3,4,5,6-Pentafluorobenzenesulfonyl chloride, 98+%
CAS: 832-53-1 | C6ClF5O2S | 266.566 g/mol
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Catalog number A17676.06
also known as A17676-06
Price (USD)
62.65
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69.40Save 6.75 (10%)
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Quantity:
5 g
Price (USD)
62.65
Online Exclusive
69.40Save 6.75 (10%)
Each
Chemical Identifiers
CAS832-53-1
IUPAC Namepentafluorobenzene-1-sulfonyl chloride
Molecular FormulaC6ClF5O2S
InChI KeyUOJCTEGNHXRPKO-UHFFFAOYSA-N
SMILESFC1=C(F)C(F)=C(C(F)=C1F)S(Cl)(=O)=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to pale yellow
Assay (GC)≥98.0%
Refractive Index1.4765-1.4805 @ 20?C
FormLiquid
Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.
Solubility
Soluble in water (reacts slowly).
Notes
Moisture Sensitive. Store away from oxidizing agents, active metals and bases, water/moisture. Keep the container tightly closed in a cool, dry place. Store under inert gas.
Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.
Solubility
Soluble in water (reacts slowly).
Notes
Moisture Sensitive. Store away from oxidizing agents, active metals and bases, water/moisture. Keep the container tightly closed in a cool, dry place. Store under inert gas.
RUO – Research Use Only
General References:
- Zhao-Qian Liu.; Zhi-Rong Tan.; Dan Wang.; Song-Lin Huang.; Lian-Sheng Wang.; Hong-Hao Zhou. Simultaneous determination of fluoxetine and its metabolite p-trifluoromethylphenol in human liver microsomes using a gas chromatographic-electron-capture detection procedure.J Chromatogr B Analyt Technol Biomed Life Sci.2002,769(2), 305-311.
- A Sentissi.; M Joppich.; K O'Connell.; A Nazareth.; R W Giese. Pentafluorobenzenesulfonyl chloride: a new electrophoric derivatizing reagent with application to tyrosyl peptide determination by gas chromatography with electron capture detection.Anal Chem.1984,56(13), 2512-2517.
- S J Asghar.; G B Baker.; G A Rauw.; P H Silverstone. A rapid method of determining amphetamine in plasma samples using pentafluorobenzenesulfonyl chloride and electron-capture gas chromatography.J Pharmacol Toxicol Methods.2001,46(2), 111-115.