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(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine
(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine
(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine
(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine
Thermo Scientific Chemicals

(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine

CAS: 485-71-2 | C19H22N2O | 294.40 g/mol
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100 g
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Catalog number A18796.22
also known as A18796-22
Price (USD)
206.65
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229.00
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Quantity:
100 g
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Price (USD)
206.65
Online Exclusive
229.00
Save 22.35 (10%)
Each
Chemical Identifiers
CAS485-71-2
IUPAC Name{5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)methanol
Molecular FormulaC19H22N2O
InChI KeyKMPWYEUPVWOPIM-UHFFFAOYNA-N
SMILESOC(C1CC2CCN1CC2C=C)C1=C2C=CC=CC2=NC=C1
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SpecificationsSpecification SheetSpecification Sheet
Loss on Drying≤1.0% (105?C, constant wt.)
FormCrystals or powder or crystalline powder
CommentMay contain up to 5% Quinine
Optical Rotation-110? ± 5? (c=1 in ethanol)
Appearance (Color)White to cream
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It finds its uses as an antimalarial compound. It is a lysosomotropic agent, inhibits Plasmodium falciparum, interferes with ferriprotoporphyrin formation and is a weak SERT inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It finds its uses as an antimalarial compound. It is a lysosomotropic agent, inhibits Plasmodium falciparum, interferes with ferriprotoporphyrin formation and is a weak SERT inhibitor.

Solubility
Insoluble in water. Soluble in alcohol and chloroform.

Notes
Light Sensitive. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Barennes H.; Verdier F.; Clavier F.; Pussard E. Pharmacokinetics of Quinimax suppositories in children with malaria: preliminary study.Clin. Drug Invest.;1999,17287-291.
  2. J M Karle.; I L Karle.; L Gerena and W K Milhous Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum.Antimicrob. Agents Chemother.1992,36(7), 1538-1544.