Gibco® FluoroBrite™ DMEM features a background fluorescence that is comparable to PBS and 90% lower than that emitted by standard phenol red–free DMEM. Formulated to include the required nutrients for routine cell culture when supplemented with 10% fetal bovine serum and 4 mM L-glutamine or GlutaMAX™ Supplement, FluoroBrite™ DMEM is designed to enhance the signal-to-noise ratio of fluorophores, enabling researchers to visualize even the weakest fluorescent events in an environment that promotes optimum cell health. Additional features include:
• Enhancement of fluorescence signal during live-cell imaging • DMEM-based to help preserve cell health
Live-cell fluorescence microscopy is an essential technique for the visualization of fundamentally important and physiologically relevant biological events. A key challenge with this technique is the ability to image weak fluorophores without causing cell damage, photobleaching, or undesirable changes to cell health. FluoroBrite™ DMEM helps address these issues.
For Research Use Only. Not for use in diagnostic procedures.
Standard Serum Supplementation
Phenol Red Indicator
No Phenol Red
Sodium Pyruvate Additive
No Sodium Pyruvate
Contents & Storage
Store in refrigerator (2–8°C). Protect from light.
Cell lines cultured in FluoroBrite™ DMEM and standard DMEM display comparable long-term growth
Detection of hypoxic conditions at the core of spheroid using Image-iT® Hypoxia Reagent
Detection of hypoxic conditions in spheroids of MCF7 using Image-iT® Hypoxia Reagent
FluoroBrite™ DMEM compared to standard phenol red–free DMEM