2-Benzyloxyphenol is used in the synthesis of 2-(benzyloxy)hydroquinone and also used to prepare sequential polypeptides.It is used as reagent for synthesis of multidentate chelating ligands. It is also used in chemicals, pharmaceutical research and also acts a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Benzyloxyphenol is used in the synthesis of 2-(benzyloxy)hydroquinone and also used to prepare sequential polypeptides.It is used as reagent for synthesis of multidentate chelating ligands. It is also used in chemicals, pharmaceutical research and also acts a pharmaceutical intermediate.
Solubility
Soluble in alcohol, benzene, and diethyl ether. Insoluble in water.
Notes
Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
General References:
- Sumida, Y.; Harada, R.; Kato-Sumida, T.; Johmoto, K.; Uekusa, H.; Hosoya, T. Boron-Selective Biaryl Coupling Approach to Versatile Dibenzoxaborins and Application to Concise Synthesis of Defucogilvocarcin M. Org. Lett. 2014, 16 (23), 6240-6243.
- Armspach , D.; Matt, D. Methylated cyclodextrins as preorganisation platforms for the synthesis of multidentate chelating ligands aimed at transition metal coordination and industrially relevant catalysis. C. R. Chim. 2011, 14 (2-3), 135-148.
- Ribeiro da Silva, M. A. V.; Lobo Ferreira, A. I. M. C.; Cimas, A. Experimental and computational study on the molecular energetics of benzyloxyphenol isomers. J. Chem. Thermodyn. 2011, 43 (12), 1857-1864.
- Lee, W-G.; Gallardo-Macias, R.; Frey, K. M.; Spasov, K. A.; Bollini, M.; Anderson, K. S.; Jorgensen, W. L. Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group. J. Am. Chem. Soc. 2013, 135 (44), 16705-16713.