Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR.
AuthorsTian F, Zhu CH, Zhang XW, Xie X, Xin XL, Yi YH, Lin LP, Geng MY, Ding J,
JournalMol Pharmacol
PubMed ID17565003
'Vascular endothelial growth factor (VEGF) signaling pathway is essential for tumor angiogenesis and has long been recognized as a promising target for cancer therapy. Current view holds that physical interaction between alpha(v)beta(3) integrin and kinase insert domain-containing receptor (KDR) is important in regulating angiogenesis and tumor development. We have reported ... More
Increase in phagocytosis after geldanamycin treatment or heat shock: role of heat shock proteins.
AuthorsVega VL, De Maio A
JournalJ Immunol
PubMed ID16210633
'The response to injury is activated at the systemic and cellular levels. At the systemic level, phagocytosis plays a key role in controlling infections and clearing necrotic and apoptotic cells. The expression of heat shock proteins (Hsp), which is a well-conserved process, is a major component of cellular response to ... More
A novel mechanism for the formation of actin-filament bundles by a nonprocessive formin.
AuthorsMichelot A, Derivery E, Paterski-Boujemaa R, Guérin C, Huang S, Parcy F, Staiger CJ, Blanchoin L,
JournalCurr Biol
PubMed ID17027489
Actin-filament bundles (or cables) have a structural role during cell division and morphogenesis, but also serve as important
Two distinct distributions of F-actin are present in the hyphal apex of the oomycete Achlya bisexualis.
AuthorsYu YP, Jackson SL, Garrill A
JournalPlant Cell Physiol
PubMed ID15047875
We show that two distinct distributions of F-actin are present in the hyphal apex of the oomycete Achlya bisexualis, that have been chemically fixed with a combination of methylglyoxal and formaldehyde and stained with Alexa phalloidin. In approximately one half of the hyphae examined, an F-actin depleted zone within the ... More
Controlling the behaviour of Drosophila melanogaster via smartphone optogenetics.
Authors
JournalSci Rep
PubMed ID33077824
Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes.
Authors
JournalStem Cell Reports
PubMed ID32470326
Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells.
Authors
JournalCurr Biol
PubMed ID29398219
Light needle microscopy with spatially transposed detection for axially resolved volumetric imaging.
Authors
JournalSci Rep
PubMed ID31406209
In situ Study Unravels Bio-Nanomechanical Behavior in a Magnetic Bacterial Nano-cellulose (MBNC) Hydrogel for Neuro-Endovascular Reconstruction.
Authors
JournalMacromol Biosci
PubMed ID30451373
Combined heterogeneity in cell size and deformability promotes cancer invasiveness.
Authors
JournalJ Cell Sci
PubMed ID34415035
Bacterial Nanocellulose Magnetically Functionalized for Neuro-Endovascular Treatment.
Authors
JournalMacromol Biosci
PubMed ID28116837
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Authors
JournalHum Mol Genet
PubMed ID31067307
A promising biodegradable magnesium alloy suitable for clinical vascular stent application.
Authors
JournalSci Rep
PubMed ID28397881
A new agarose-based microsystem to investigate cell response to prolonged confinement.